The article does a good job explaining where the LOBES OF BRAIN are tied to BRAIN IMPLANTS like COCHLEAR, RETINAL, AND NOSE/SINUS. We discuss whether these implants tied to specific body functions are AUTONOMOUS or INVOLUNTARY vs VOLUNTARY NERVOUS SYSTEM----
We will segue from discussing things like BATTERY TECHNOLOGY for implants to CLINICAL TRIALS tied to these implants. One thing we notice about these trials taking place during CLINTON/BUSH/OBAMA-----these trials were SELF-REGULATING---meaning no oversight was given with the US FEDERAL FUNDING----if a trial was led by BARBER SURGEONS and not PHYSICIANS we would and did get CRIMINAL AND CORRUPT activities throughout these trials.
It is important to understand the basic difference in our NERVOUS SYSTEM-----those nerves needing thought for movement vs those nerves that work automatically with no thought. Our 5 SENSES are AUTONOMOUS-----they work without our thinking.
'Nervous system - Reflex Action, Voluntary and Involuntary Action
Reflex action: Reflex action or reflex is an involuntary action in response to a stimulus. Voluntary action: When an action is produced with the involvement of thoughts,... Involuntary action: Actions which take place without consciousness or willingness of an individual are ...'
I have discussed having a COCHLEAR IMPLANT-----HEARING IS AUTONOMOUS-----I have discussed RETINAL IMPLANT----SEEING IS AUTONOMOUS------I have discussed NOSE IMPLANT----SMELLING IS AUTONOMOUS.
I have these several months since JANUARY 2019 having been made aware I am being illegal surveilled by cameras inside my living space and inside my HEAD indicated how FEEDBACK and illusion in the form of SUBLIMINAL MESSAGING is controlling most of this FAKE DATA from these HEAD/BODY IMPLANTS.
I refer to three time periods in which any IMPLANT DEVICE could have been implanted. First, 2006 -----where I feel I had a COCHLEAR IMPLANT installed. 2007 where having been knocked out could have had a RETINAL IMPLANT. In 2010---2012 another knock out could have been that UPDATE OF IMPLANTS with latest research product and a NOSE/SINUS IMPLANT.
We did the timetable making it clear these dates correspond to CLINICAL TRIALS tied to these IMPLANTS.
This discussion looking at RETINAL CLINICAL TRIALS are valid for COCHLEAR AND NOSE/SINUS IMPLANTS CLINICAL TRIALS.
I left SEATTLE due to SADD-------depression from lack of sun refusing to take PROZAC as that current employer requested----because I do not like PHARMA -----
'Prozac Lawsuits - drugwatch.com
Prozac Lawsuits. Its litigation history is controversial. Lawsuits accuse Eli Lilly of failing to warn about Prozac side effects and using questionable marketing practices. Beginning in the 1990s, the drug giant faced lawsuits alleging it failed to warn that the drug could cause violent behaviors and suicidal thoughts'.
What I got as a result was a HITTING placing me in continuous CLINICAL TRIALS which are PHYSICALLY HARMFUL AND/OR DEADLY.
Retina Implant Pilot Trial to Evaluate Safety & Efficacy in Blind Patients Having Degenerated Photo-receptors
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00515814
Recruitment Status : Completed
First Posted : August 14, 2007
Last Update Posted : June 9, 2011
Retina Implant AG
Information provided by:
Retina Implant AG
The outcome of this trial will reveal the possibilities of the retinal implant to improve the situation of patients with hereditary retinal blindness caused by degenerations of the outer retina. This pilot study will give important information on safety and efficacy of sub-retinal implants.
Condition or disease Intervention/treatment Phase
Retinitis PigmentosaDevice: Retina implant is surgically placed into subretinal positionNot Applicable
Although the design of the chip with a possible resolution of up to 1500 image points has the potential of providing object recognition, the quality of the image transmitted in this first human application cannot be foreseen. On the other hand clinical experience teaches us that even bare light recognition improves mobility of patients because of the ability to localize bright light sources such as windows or lamps.
One of the first things I NOTICE in the timing of these IMPLANT CLINICAL TRIALS which do indeed seem to match these periods where installation likely occurred------the PATIENTS being said to VOLUNTEER ---CONSENT were people with SERVERE disability------BLIND, DEAF, NO SENSE OF SMELL.
My lawsuit against NOSY NEIGHBORS AND THE GANG is based upon the fact I was TOTALLY HEALTHY-----any deficit was MINOR not enough to quality for a CLINICAL TRIAL. I was used as a NORMAL CONTROL for these trials------people don't usually volunteer for EXPERIMENTAL RESEARCH DEVICES having never been exposed to HUMANS.
The other issue I would like our US 99% WE THE PEOPLE to understand------these clinical trials always seem to have several HUMANS as PATIENTS-----when in fact these ILLEGAL IMPLANTS are happening ALL THE TIME to people NOT KNOWING---JUST LIKE ME.
First Results from Retinal Implant Clinical Trial Presented by UPMC Ophthalmology Expert | Regenerative Medicine at the McGowan Institute
Regenerative Medicine: applying tissue…'
Lastly, we want to point out----I live in BALTIMORE----the only place I have experienced HOSPITAL access for such IMPLANTATIONS ---while some of these STUDIES---TRIALS are occurring in PITTSBURG----PHILADELPHIA------STANFORD CALIFORNIA.
A CITIZEN CAN BE TAGGED WITH THESE IMPLANTS AND NOT KNOW IT---AND NOT BE IN THE CITY WHERE THE MAIN TRIAL IS HEADQUARTERED.
So, BALTIMORE could be a SATELLITE CLINICAL TRIAL SIGHT-----
Study Type : Interventional (Clinical Trial) Estimated Enrollment :
15 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: A Prospective Open Pilot Study With Functional Placebo-control to Evaluate the Efficacy and Tolerability/Safety of a Subretinal Implant in Blind Patients in Accordance With ICH/GCP
Guidelines Study Start Date : September 2005
Actual Primary Completion Date : December 2009
Actual Study Completion Date : December 2009
First Results from Retinal Implant Clinical Trial Presented by UPMC Ophthalmology Expert
By: The McGowan Institute For Regenerative Medicine | Category: News Archive, Vision | November 28, 2018
Promising first results from the clinical feasibility trial of PRIMA, a wireless retinal implant designed to help restore useful vision in patients with advanced atrophic dry age-related macular degeneration (AMD), were presented recently at the American Academy of Ophthalmology 2018 annual meeting held in Chicago. The presentation was acknowledged as the “Best Paper” of Retina Session II at the meeting.
The trial is led in Paris – and now actively enrolling in Pittsburgh – by José Alain Sahel, MD, director of the UPMC Eye Center and Eye and Ear Foundation chair of ophthalmology at the University of Pittsburgh School of Medicine. Dr. Sahel also is the director of the Institut de la Vision in Paris and is an affiliated faculty member of the McGowan Institute for Regenerative Medicine.
“We are pleased with the results from the PRIMA trial showing the chip can be safely implanted in patients without affecting their existing vision. Furthermore, patients experienced positive improvements in their ability to correctly detect visual patterns, and we expect these improvements to continue as they progress in their rehabilitation program,” said Dr. Sahel.
The UPMC feasibility trial of PRIMA currently is enrolling patients. It is the first and only site in the United States where this technology will be evaluated. Five patients will enroll in the study, which will be similar to the French feasibility trial.
AMD is the leading cause of vision loss in people older than 50 and affects approximately 14 million people in the United States. The aging baby boomer population is expected to lead to a significant increase in the prevalence of AMD, which is characterized by a progressive loss of vision, and an increasingly larger blurred area near the center of vision. “Dry” AMD, which accounts for 80 to 90 percent of cases, has no curative treatment available.
The current clinical trial, led by Dr. Sahel in Paris, France, is evaluating the safety and feasibility of the PRIMA bionic vision system, developed by Paris-based Pixium Vision in partnership with Stanford University and the Institut de la Vision in Paris. The PRIMA system consists of a miniature wireless photovoltaic chip implanted beneath the retina of patients with advanced atrophic dry AMD, along with special augmented reality glasses worn by the patient that contain a miniature camera and projector.
The chip acts like a tiny solar panel, made up of hundreds of tiny electrodes that convert infrared light signals from the projector to electrical signals that are carried by the optic nerve to the brain.
After receiving the implant, patients undergo an intensive rehabilitation program that trains their brains to understand and interpret the signals from the implant.
Five patients were enrolled between December 2017 and June 2018 in Paris, each with significant vision loss in one eye and remaining useful vision in the other.
The PRIMA implants were placed through a minimally invasive procedure. The implant remained stable under the retina and patients did not experience any peripheral vision loss as a result of the procedure. During the rehabilitation program, most patients have correctly identified various visual patterns, including bars, letters and numbers. The patients continue to be followed, and six-month progress results are expected by the end of the year.
The clinical trials in Paris and Pittsburgh are sponsored by Pixium Vision, based in Paris. The PRIMA implant was invented by Daniel Palanker, PhD, professor of ophthalmology at Stanford University, and licensed and developed by Pixium. Dr. Sahel is a co-founder of Pixium Vision.
Below we see what created the conditions for a need TO HIT---HIT HARD-----PSYCHO-SEXUAL TORTURE to scare---to ruin ---to bring me to dispare-----sending me to PYSCH WARD.
The NOSY NEIGHBOR AND THE GANG talk mirrors the dates of CLINICAL TRIALS for the same IMPLANTS I received since 2006----2007-----2010 or 2012.
We see the START DATE as MARCH 2019-----the HITTING started in JANUARY 2019. This is why the HITTING became so strong, threatening------with goals of being DISABILING.
Study Type : Interventional (Clinical Trial) Actual Enrollment : 0 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Early Feasibility Study of the RETINA IMPLANT Alpha AMS in Blind Patients With Retinitis Pigmentosa Estimated
Study Start Date : March 2019
Estimated Primary Completion Date : July 2025 Estimated Study Completion Date : July 2025'
I will be requesting CONSENT FORMS FOR PARTICIPATION from Baltimore institutions but also these HEADQUARTERS for clinical trials tied to these IMPLANT DEVICES in my BODY and HEAD.
Below we see MAY 2019 as the last date for the trial below. I was experiencing serious PSYCHO-SEXUAL TORTURE and threats of HOMELESSNESS ----being sent to a SHELTER-----up until MAY 2019. When I did succumb to these NOSY NEIGHBORS AND THE GANG hired by global banking 1% CORPORATIONS ----in this case MEDICAL CORPORATIONS.......things calmed down and this is when I received the designation of being RUINED AND SENT DOWN THE RIVER STYX.
United States, Pennsylvania
Wills Eye Hospital
Philadelphia, Pennsylvania, United States, 19107
Sponsors and Collaborators
Retina Implant AG
Study Director:Jay Federman, MD
Wills Eye Hospital
Stingl K, Schippert R, Bartz-Schmidt KU, Besch D, Cottriall CL, Edwards TL, Gekeler F, Greppmaier U, Kiel K, Koitschev A, Kühlewein L, MacLaren RE, Ramsden JD, Roider J, Rothermel A, Sachs H, Schröder GS, Tode J, Troelenberg N, Zrenner E. Interim Results of a Multicenter Trial with the New Electronic Subretinal Implant Alpha AMS in 15 Patients Blind from Inherited Retinal Degenerations. Front Neurosci. 2017 Aug 23;11:445. doi: 10.3389/fnins.2017.00445. eCollection 2017.
Edwards TL, Cottriall CL, Xue K, Simunovic MP, Ramsden JD, Zrenner E, MacLaren RE. Assessment of the Electronic Retinal Implant Alpha AMS in Restoring Vision to Blind Patients with End-Stage Retinitis Pigmentosa. Ophthalmology. 2018 Mar;125(3):432-443. doi: 10.1016/j.ophtha.2017.09.019. Epub 2017 Oct 27.
Responsible Party:Wills Eye
ClinicalTrials.gov Identifier:NCT03629899 History of Changes
Other Study ID Numbers:17-645
First Posted:August 14, 2018 Key Record Dates
Last Update Posted:May 10, 2019
Last Verified:May 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD:Undecided
Studies a U.S. FDA-regulated Drug Product:No
Studies a U.S. FDA-regulated Device Product:Yes
Device Product Not Approved or Cleared by U.S. FDA:No
Pediatric Postmarket Surveillance of a Device Product:No
Keywords provided by Wills Eye:
Inherited Retinal Degeneration
Additional relevant MeSH terms:
Eye Diseases, Hereditary
Genetic Diseases, Inborn
I WAS THAT 50 AND OLDER BABY BOOMER.
Information from the National Library of Medicine
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: 50 Years and older (Adult, Older Adult)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
• Blind RP patients with LP or NLP identified in both eyes using a photoflash test.
(NLP inclusion is defined as participants who at screening give less than 9 correct answers out of 20 trials to the photoflash test; LP inclusion is defined as participants who at screening give 9 or more correct answers out of 20 trials to the photoflash test)
- Pseudophakia for at least 3 months prior to entrance into study.
- Central visual function of 12 years / lifetime or greater with a history of reading vision in the eye to be implanted.
- Fluorescein angiography showing retinal vascular perfusion in all four quadrants of macula.
- Fifty (50) years of age or older at time of enrollment.
- Evidence of inner retinal function (ganglion cells and optic nerve function) by EEP test identified by the ability to elicit phosphene thresholds.
- ERG showing rod and cone non-function.
- Willing and able to give written informed consent and participate in ongoing follow-up.
- Ophthalmic conditions other than RP with relevant effect upon visual function (e.g., glaucoma, optic neuropathies, trauma, diabetic retinopathy, retinal detachment, macular degeneration, cystoid macular edema, MS) with the addition of tobacco, alcohol abuse and retinotoxic drugs e.g. plaquenil and thorazine.
- Any other ocular disease that affects retina and / or optic nerve function.
- Opacification of ocular structures that prevent clear image transmission.
- Cystoid macular edema within target region for implantation shown via Optical Coherence Tomography (OCT).
- Retina detected as too thin as shown via OCT (<100 μm) to expect required functionality of inner retina and /or OCT shows no layering of the inner retina in the central region.
- Scar tissue (e.g., epiretinal, intraretinal, subretinal, macular pucker) within target region for implantation.
- Heavily clumped pigmentation at posterior pole (would interfere with image transmission to vision chip).
- Anterior segment pathology that interferes with clear visualization of the retina (e.g., presence of cloudy or scarred cornea and / or papillary membrane) that cannot be resolved prior to entrance into study.
- Amblyopia reported earlier in life for eye to be implanted.
- Systemic diseases that might imply considerable risks with regard to the surgical interventions and anesthesia (e.g., cardiovascular / pulmonary diseases, severe metabolic diseases).
- Any condition and / or allergic contraindication to pre-operative, intra-operative, and post-operative medication.
- Health problems where general anesthesia is contraindicated.
- Disease or conditions that would probably limit life expectancy to less than 1 year from screening.
- Orbital deformity that would interfere with surgical implantation that could not be resolved prior to entrance into study.
- Patients with plastic intra-ocular lenses, or other materials, that would interact with silicone oil.
- Women who are pregnant or nursing, or women of childbearing potential who are not willing to use a medically acceptable means of birth control for the duration of the study, or women unwilling to perform a pregnancy test before entering the study.
- Neurological and / or psychiatric diseases (e.g., Parkinson, epilepsy, MS, depression or severe anxiety).
- Lack of cognitive and / or emotional ability (e.g., depression or severe anxiety) limiting participation as assessed by psychiatric evaluation.
- Participation in another interventional clinical trial within the past 30 days.
- The need for regular administration of anticoagulants, platelet aggregation inhibitors or analgesics containing acetylsalicylic acid.
- Disease or conditions that likely require regular use of MRI or other similar imaging technology that emits electromagnetic radiation.
- Patients unwilling to avoid participating in vigorous sports or activities with a high risk of a head injury.
- Patients unwilling to avoid security-scanning devices that would result in a full body, manual search.
- Ability to perceive form or motion under optimal conditions (largest size, brightest lighting, highest contrast, etc.) of form and motion testing as tested by BaLM, BaGA, and Landolt C.
- Patients with hearing deficits and cochlear implants or patients who may be implanted with cochlear implants in the near future.
- Patients undergoing or requiring medical treatments generating induced currents in the area of the implant such as electrosurgery, diathermy, neurostimulation, electroconvulsive therapy, ionizing radiation therapy, therapeutic ultrasound.
- Subjects with no active immunization status against organisms causing meningitis.
One of the ways HOSTING SERVER NOSY NEIGHBORS worked hard to me INSTITUTIONALIZED-----was to create that GROUP SPEAK AND CHATTER surrounding me being CRAZY-----MENTALLY------VIOLENT---DANGEROUS sending in the POLICE to take me to psych ward.
As I listened to FEEDBACK coming from NOSY NEIGHBORS AND THE GANG and from PUBLIC SURVEILLANCE almost ALL of the below conditions to categorize a human as MENTALLY INCOMPETENT --------were being used in PSYCHO---SEXUAL TORTURE.
GROUP SPEAK AND CHATTER SAYING:
I had cold, clammy hands
I had obsessive compulsive behavior with touching my nose
I had TIC DISORDER because I tapped or clapped while listening or thinking about MUSIC.
I had a skin-picking disorder when I was itchy from dry skin.
My hands were trembling when I extended arms.
I had FINGER FLICKING because I was rubbing two finger together tied to touching my nose.
So, taken together HOSTING SERVER NOSY NEIGHBOR using the illegal streaming 24/7 black market video of me inside my LIVING SPACE-----they diagnosed me as
GENERALIZED ANXIETY DISORDER
OBSESSIVE COMPULSIVE DISORDER
ADHD ----ATTENTION DEFICIT DISORDER
IMPULSE CONTROL DISORDER
AUTISM SPECTRUM DISORDER.
Since I have NONE OF THE ABOVE-----HOSTING SERVER NOSY NEIGHBOR had to turn the dogs loose---the PORN MULES-----to create a FAKE PROFILE.
By the way----all that NOSE TOUCHING and feeling like my NOSE was electrified and constantly dealing with mucus---------was what I have determined to be a NOSE/SINUS IMPLANT
Side-effects of cochlear implant surgery Bleeding and swelling at the site of the implant. Infection in the area of the implant. Ringing in the ears ( tinnitus). Dizziness or vertigo'.
Ergo, the VERTIGO I was experiencing.
16 Hand behaviors in Mental Disorders (Psychopathology)
Guidelines according DSM-5, DSM IV & ICD-10
AUGUST 3, 2014
16 Hand behaviors in mental disorders according DSM 5 (2013), DSM IV (1994), and ICD-10 (1992):
• I - Cold, clammy hands: Generalized Anxiety Disorder, Social Phobia (Social Anxiety Disorder)
• II - Hand-washing compulsions: Obsessive Compulsive Disorder (OCD)
• III - (Out of control) finger tapping/fidgeting: Attention Deficient Hyperactivity Disorder (ADHD)
• IV - Athetoid finger movements: Tic Disorders
• V - Hair pulling disorder: Trichotillomania (Impulse Control Disorder)
• VI - Skin picking disorder: Excoriation (Impulse Control Disorder), Amphetamine-Induced Psychotic Disorder
• VII - Tremor of outstretched hands: withdrawal states (related to e.g.: alcohol, cannabis, sedative-hypnotic)
• VIII - Hand flapping/finger flicking: Autism Spectrum Disorder, Delirium
• IX - Hand biting: Autism Spectrum Disorder, Stereotypic Movement Disorder
• X - Hand wringing: agitation in Major Depressive Episode, Rett's syndrome (Autism Spectrum Disorder)
• XI - Poor handwriting: Specific Learning Disorder with Impairment in Written Expression
• Five other hand behaviors associated with psychopathology
Hand behaviors (read: hand gestures, hand movements, hand signs, etc.) in different cultures may imply different meanings, this is even seen in the deaf cultures around the world which communicate using different hand sign languages. But sometimes hand behaviors are recognized to have univeral value. This is for example illustrated by the role of hand behaviors in the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV + DSM-5, presented in 2013 by the American Psychiatric Association) & the International Statistical Classification of Diseases and Related Health Problems (ICD-10 chapter V, presented in 1992 bij the WHO), which are today recognized to represent the world's leading sources for the classification of psychiatric disorders. Interestingly, both diagnostic tools make various references to body language behaviors involving the hands. This article presents an overview of the most significant hand beviors mentioned in both systems, which include a wide range of extraordinary disorders, e.g social phobia, OCD, ADHD, autism, depression & psychotic disorders!
Behavior specialists in psychology are generally more interested in answering the question 'why do people use hand gestures?' instead of answering the question 'what is the meaning of a specific gesture?', because the context is usually decisive regarding the motives why people start using body language. Therefore it is crucial to understand that the listed hand behaviors in isolation (from other significant contextual clues) should not get associated with any mental disorder directly. This implicates that context should always become decisive in the process of assessing the significance of these hand behaviors!
Cold, clammy hands can represent a clue for a mental disorder, e.g. Social Phobia (Social Anxiety Disorder).
I - COLD, CLAMMY HANDS: Generalized Anxiety Disorder, Social Phobia (Social Anxiety Disorder)
According the DSM IV represent cold clammy hands (combined with shaky hands/trembling hands/tremors) an observable sign for anxiety, which explains why it became associated with Generalized Anxiety Disorder [DSM-IV code: 300.02]. In DSM 5 & ICD-10 this hand behavior is not explicitly mentioned, but there is consensus that cold, clammy/sweaty hands & shaking hands represent a classic observable sign for anxiety.
Hand-washing compulsions can represent a clue for a mental disorder, e.g. Obsessive Compulsive Disorder (OCD).
II - Hand-washing compulsions: Obsessive Compulsive Disorder (OCD)
According the DSM-IV & DSM 5 represent hand-washing compulsions (resulting in raw skin due to contamination fear) is recognized as a typical feature of Obsessive Compulsive Disorder [DSM-IV & DSM 5 code: 300.3]; fear of being contaminated by shaking hands or by touching objects others have touched is also a typical example of accessory behavior. In ICD-10 hand washing is also described as a typical behavior in Obsessive Compulsive Disorders [ICD-10 code: F42].
Excessive finger tapping/fidgeting can represent a clue for a mental disorder, e.g. Attention Deficit Hyperactivity Disorder (ADHD).
III - (Out of control) FINGER TAPPING/FIDGETING: Attention Deficit Hyperactivity Disorder (ADHD)
According the DSM-IV & DSM 5 can out of control hand tapping (or finger fidgeting with- or without objects) represent a clue for ADHD [DSM-IV & DSM 5 code: 314.01]. In ICD-10 this disorder is not listed (yet).
Alternatively, according DSM-IV & DSM 5 out of control finger fiddling, striking fingers, playing with hands or hand waving represents a clue in Stereotypic Movement Disorder [DSM-IV code: 307.3], a disorder that interferes with normal activities or results in bodily injury. In ICD-10 finger flicking represents a feature in Stereotypic Movement Disorder [ICD-10 code: F98.4]. NOTICE: The person may develop methods of self-restraint (such as: holding hands inside shirts, trousers, or in pockets) in an attempt to control the self-injurious behaviors.
Here's a detailed report about the role of finger tapping in ADHD:
Tapping Fingers Point to ADHD.
Athetoid finger movements can represent a clue for a mental disorder, e.g. Tic Disorders.
IV - ATHETOID FINGER MOVEMENTS: Tic Disorders
According DSM-IV so-called atheoid finger movements (which are characterized by slow, involuntary, convoluted, writhing movements of especially the fingers or hands) represent a clue for Tic Disorders [DSM-IV code: 307.20]. In ICD-10 this disorder is not listed.
The video below a typical example of athetoid finger movements:
Hair pulling disorder (trichotillomania) can represent a clue for a mental disorder, e.g. Trichotillomania (Impulse Control Disorder).
V - HAIR PULLING DISORDER: Trichotillomania (Impulse Control Disorder)
According the DSM-IV can excessive hair-pulling behavior (resulting in noticable hair loss + distress or impairment in social/occupational functioning) represent a clue for an Impulse Control Disorder named Trichotillomania [DSM IV code: 312.39]. In ICD-10 Trichotillomania is classified under the Habit & Impulse Disorders [ICD-10 code: F63.3].
This (awesome) BBC video below concerns a selfie project documenting a young woman's battle with her trichotillomania hair-pulling disorder; the original video has been watched almost six million times:
Skin picking disorder (excoriation) can represent a clue for a mental disorder, e.g. Excoriation (Impulse Control Disorder).
VI - SKIN PICKING DISORDER: Excoriation (Impulse Control Disorder)
In DSM 5 a seperate category has been created for skin picking (resulting in significant distress or impairment in social/occupational functioning), which represents a clue for an OCD related impulse control disorder named excoriation [DSM 5 code: 698.4]. In ICD-10 this disorder is not listed (yet).
In DSM-IV excoriation was also listed for Amphetamine-Induced Psychotic Disorder [DSM-IV code: 292.12].
Tremors of the outstretched hands can represent a clue for a mental disorder, e.g. withdrawal states (alcohol, cannabis) or sedative-hypnotic withdrawal state.
VII - TREMORS OF OUTSTRETCHED HANDS: Medication-Induced Postural Tremor, withdrawal states (related to e.g: alcohol, cannabis, sedative-hypnotic)
According the DSM 5 (+ DSM-IV) a so-called condition named Medication-Induced Postural Tremor [DSM code: 333.1] - such as: Alcohol Withdrawal [DSM-IV code: 291.8] & Sedative, Hypnotic, or Anxiolytic Withdrawal [DSM-IV code: 292.0] - is featured with a tremorn with a regular, rhythmic oscillation of the limbs (most commonly hands and fingers) with a frequency of between 8 and 12 cycles per second. It is most easily observed when the hands are stretched out. This is a typical phenomenon due to e.g. antidepressant medications & antipsychotics. In the ICD-10-CM system, this hand behavior is known under the same name: Medication-Induced Postural Tremor [ICD-10 code: G25.1]; also, the same type of tremors also likewisely gets associated with withdrawal states related to alcohol [ICD-10 code: F10.3] or cannabis [ICD-10 code: F12.3], or due to a sedative-hypnotic withdrawal state [ICD-10 code: F13.3].
Hand flapping can represent a clue for a mental disorder, e.g. Autism Spectrum Disorder.
VIII - HAND FLAPPING/FINGER FLICKING: Autism Spectrum Disorder, Delirium
According the DSM 5 is hand flapping (or: repetitive hand shaking, hand clappping, finger flicking, finger twisting) a common behavior assocated with Autims Spectrum Disorder [DSM 5 code: 299.00] (in DSM IV hand flapping & finger twisting was listed for Autistic Disorder [DSM-IV code: 299.00] & Asperger's Disorder [DSM-IV code: 299.80]). In the ICD-10 system, hand flapping is likewisely associated with Pervasive Developmental Disorders, including: Childhood Autism [ICD-10 code: F84.0] and overactive disorder associated with mental retardation and stereotyped movements [ICD-10 code: F84.4].
In rare cases hand flapping may also gets associated with Delirium due to a general medical condition [DSM IV & 5 code: 93.0], specified as 'Asterixis': the flapping movement of the hyperextended hands, was originally described in hepatic encephalopathy but may also be found in association with other causes of Delirium; this concerns a condition that can be recognized as a tremor variant.
In the video below peditrician Dr. Sara Connolly explains when to get worried about hand flapping in children:
Hand biting can represent a clue for a mental disorder, e.g. Autism Spectrum Disorder, Stereotypic Movement Disorder.
IX - HAND BITING: Autism Spectrum Disorder, Stereotypic Movement Disorder
According the DSM 5 is hand biting a well-known behavior assocated with Autism Spectrum Disorder [DSM 5 code: 299.00] (in DSM IV hand biting was listed for Autistic Disorder [DSM IV code: 299.00]).
Hand biting also gets listed as a common feature in Stereotypic Movement Disorder [DSM IV & DSM 5 code: 307.3].
Hand biting was not yet listed in the 1993's ICD-10 system, however later it became listed as 'habitual hand biting' inside a long list of other and unspecified special symptoms or syndromes, not elsewhere classified [ICD-10 code: 307.9].
Hand wringing can represent a clue for a mental disorder, e.g. Rett's syndrome (autism spectrum disorder), agitation in Major Depressive Depisode.
X - HAND WRINGING: Rett syndrome (Autism Spectrum Disorder), agitation in Major Depressive Episode
According the DSM-IV hand wringing (which may look like hand washing, representing midline hand movements) can represent a very typical clue for stereotyped hand movements in Rett Syndrome [DSM-IV code: 299.80]. In ICD-10 hand wringing is also listed as a typical behavior in Rett syndrome [ICD-10 code: F84.2], which became classified in DSM 5 under the Autism Specturm Disorder.
Hand writing also gets listed as a common feature in agitation in Major Depressive Episode [DSM IV code: 296.40].
The video below present an example of hand wringing in a young girl with Rett syndrome:
Poor handwriting can represent a clue for a mental disorder, e.g. Specific Learning Disorder with Impairment in Written Expression.
XI - (EXCESSIVELY) POOR HANDWRITING: Specific Learning Disorder with Impairment in Written Expression
According DSM 5 excessively poor handwriting (in the presence of other impairment in written expression) can represent a clue for a Specific Learning Disorder with Impairment in Written Expression [DSM 5 code: 315.2; in DSM-IV it was named: disorder of written expression]. In ICD-10 it is named: Disorder of Written Expression [ICD-10 code: F81.81].
A disorder in spelling or handwriting alone, in the absence of other difficulties of written expression, generally does not qualify for a diagnosis of disorder of written expression. If poor handwriting is due to impairment in motor coordination in isolation, this presents a clue for Developmental Coördination Disorder.
In the video below clinical psychologist Dr. Kimberly Williams describes the potential impact (+ cause) of a non-verbal learning disorder:
Additionally, there are a few other hand behaviors which have been associated with various types of psychopathology which have been mentioned inside the DSM IV/5 system presented by the American Psychiatric Association, or the WHO's ICD-10 system for the classification of mental disorders:
• XII- Small handwriting (micrographia) represents a sign of Neuroleptic-lnduced Parkinsonism [DSM-IV code: 332.1].
• XIII- Loss of the ability to identify objects placed in their hands by touch alone is listed in DSM-IV as a significant sign in Dementia [DSM-IV code: 294.8].
• XIV Presence of involuntary choreiform movements, typically of the hands is described in ICD-10 as a significant sign in Dementia in Huntington's disease [ICD-10 code: F02.2]. The patient may attempt to conceal them by converting them into a voluntary action.
• XV- Delayed developement of hand dominance has been associated in DSM-IV with Autistic Disorder [DSM-IV code: 299.00].
• XVI- Loss of previously acquired purposeful hand skills (between ages 5 and 30 months, with the subsequent development of characteristic stereotyped hand movements resembling hand-wringing or hand washing) has been associated in DSM-IV with Rett Syndrome [DSM-IV code: 299.80].
• XVII- Alien hand syndrome manifests in feeling that one's hand is possessed by a force outside of ones control. The syndrome typically arises after trauma to the brain, after brain surgery or after a stroke or an infection of the brain. A person with the alien hand syndrome can feel sensation in the affected hand but thinks that the hand is not part of their body and that they have no control over its movement, that it belongs to an alien [ICD-9 code: 781.8].
NOTICE: The hair pulling disorder 'trichotillomania' and the so-called 'Alien hand syndrome' are often listed among the TOP 10 weirdest mental disorders.
Read more about how the hand morphology & hand shape get associated with psychiatric disorders:
- Autism & the hand
- Schizophrenia & the hand
Hand behaviors synonyms: hand gestures - hand movements - hand signs.
My condition of ASTHMA was created by inhalation of construction particulates and has developed into CHRONIC RHINO--SINUSITIS. That RHINO-SINUSITIS is what has me TOUCHING MY NOSE------CLEARING MY NOSE-----HAVING A LOT OF MUCUS at times.
There is NOTHING psychotic about CHRONIC RHINO-SINUSITIS.
Besides the initial exposure to construction particulates-----I had that NOSE/SINUS IMPLANT-------which INFLAMES------IRRITATES------STIMULATES RELEASE OF MUCUS-----AND IT ELECTRIFIES MY NOSE.
But OK says HOSTING SERVER NOSY NEIGHBOR---we are getting IMPLANT information on how the BRAIN PROCESSES ---SMELL.
Chronic Rhino-Sinusitis and Asthma: Concept of Unified Airway Disease (UAD) and its Impact in Otolaryngology
Rakesh Singh Meena, Deepali Meena, Yogesh Aseri, B. K. Singh, and P. C. Verma
Author information Article notes Copyright and License information Disclaimer
The aim of our study is to understand the concept of unified airway disease, to know the advantage of this concept in the diagnosis and treatment of allergic rhinitis, chronic rhino-sinusitis and asthma, to know its impact on practice of otolaryngologists, to motivate the otorhinolaryngologist to apply this concept in diagnosis and treatment. This article is based on our experience on (20 cases) chronic rhino-sinusitis and asthma, and observations and results from various literatures. Implement of the concept of unified airway disease and ability to translate its principles into successful diagnostic and treatment strategies can enhance the practice of otolaryngology. The end result is the potential for improved patient care. In our study 80% cases have reduced frequency of symptoms and all (100%) cases having improved night time symptoms thus the use of short-acting beta2 agonist to control the asthma symptoms decreases.
Keywords: Unified airway disease (UAD), Chronic rhino-sinusitis (CRS), Immunoglobulin-E (IgE), Para nasal sinuses (PNS), Interleukin (IL), Short-acting beta2 agonist- salbutamol
Until recently, rhinitis and asthma have been evaluated and treated as separate disorders, but current opinion has moved toward the concept of unifying the management of these disorders. The unified airway disease (UAD) hypothesis purposes that upper and lower airway diseases are both are infections of a single inflammatory process within the respiratory tract. Synonyms of UAD include allergic rhino bronchitis and combined allergic rhino-sinusitis and asthma. IgE mediated allergic responses to inhaled allergens cause symptom of asthma and rhino-sinusitis, but there is increasing evidence of a systemic link between the lower and upper airway.
Concept of Airway
Over the course of the past two decades, the concept of inflammation involving both the upper and lower airways has become increasingly recognized and studied. When examined, asthma, allergy, and rhino-sinusitis appear to behave similarly and in conjunction with one another in many cases, suggestive of an integration of the involved areas of the airway. This pattern of similarities has given rise to the concept of the unified airway model, which, simply stated, considers the entire respiratory system to represent a functional unit that consists of the nose, paranasal sinuses, larynx, trachea, and distal lung .
The broad number of inflammatory diseases that occur within this functional unit present to a variety of specialties, including otolaryngology, pulmonology, primary care, and allergy . Similarly, literature related to this concept distributed among the literature of each of these specialties.
The model of unified airway provides conceptual framework for understanding and managing patients who have both upper and lower airway inflammatory disease. Through appreciating the relationships that exist among diseases such as otitis media, allergic rhinitis, acute and chronic rhino-sinusitis, and asthma, physicians can be more through in their diagnosis and treatment of patients who have airway disorders and can implement effective treatment strategies to decrease the burden and symptomatic expression of disease.
Criteria in Support of a Unified Airway
Patients with upper airway diseases have a higher prevalence of lower respiratory disease such as asthma, the corollary, increased prevalence of upper respiratory diseases is also found among patients with lower respiratory disease.
Interrelated patho physiological mechanism between upper and lower airway diseases exist to explain the interaction of these two disease processes treatment of one portion of the unified airway improves the symptoms in a lower portion of the respiratory system.
Proposed pathophysiological links between the upper and lower airways:
- Systemic interaction (inflammatory crosstalk): The mechanism by which communication occurs between the upper and lower airways is suggested to be via systemic inflammatory response (IL-4, IL-5, IL-13, Eotaxin, etc.,) [1, 12].
- Loss of conditioning by nose and PNS: Allergic rhinitis has adverse effects on the lower airway by the promotion of breathing through the mouth. High nasal nitric oxide concentrations (up to 100 times greater than in orally exhaled air) are thought to have antiviral, bacteriostatic, and bronchodilator effects on the lower airway (conditioning of inspired air).
- Nasobronchial reflex has also been suggested (e.g., transient bronchoconstriction resulting from irritant stimulation of nasal mucosa).
- Pharyngobronchial reflex: Irritation of the hypopharynx with sinus secretions leads to bronchoconstriction and reduction in airflow rates.
Materials and Methods
This was prospective study of 20 cases (15–60 years age group) of asthma (diagnosed by physician) having chronic rhino-sinusitis (means nasal sign/symptoms of more than 12 weeks e.g., nasal discharge, blockage, post nasal drip, hyposmia/anosmia with or without facial pain/pressure/fullness/headache). These patients were sent to ENT OPD to treat the nasal symptoms which were diagnosed as rhino-sinusitis with asthma. rhino-sinusitis was diagnosed by clinical features and radiological investigations (e.g., X-ray PNS waters view/CT scan if required).
Asthma was diagnosed by following clinical features:
- Shortness of breath
- Coughing in cold and night
- Chest tightness
All 20 cases were categorized in four groups ((1) intermittent, (2) mild persistent, (3) moderate persistent, (4) severe persistent), depending on frequency of asthma symptoms/night time symptoms/use of beta2 agonist for control of symptoms. Than rhino-sinusitis was treated medically (in 18 cases) and both medically and surgically (FESS in 2 cases). After 6 months of rhino-sinusitis treatment we compared the asthma symptoms and need of asthma medication before and after treatment of rhino-sinusitis and conclusion was made.
Observations and Results
Table 1 showing that all 20 cases were grouped in four groups depending upon severity of symptoms and requirement of short-acting beta2 agonist for symptom control. All patients in an individual group having equal severity of symptoms (depending upon frequency of symptoms and night time symptoms) so required the same amount of beta2 agonist for control of symptoms.
WHAT I AM FEELING IN MY NOSE LEADING ME TO CONSTANTLY TOUCH IT ----IS THIS ELECTRICAL STIMULATION ----NO DOUBT BEING APPLIED AT DIFFERENT TIMES OF DAY ---AT LOW OR HIGH STIMULATION.
This is how I know NOSY NEIGHBORS AND THE GANG constantly trying to HUMILIATE me calling me PSYCHO because I TOUCH MY NOSE----CLEAR MY NOSE-----have continuous periods of MUCUS which I thought may have been ALLERGIES.
NOSY NEIGHBORS AND THE GANG WORKING FOR BLACK MARKET ILLEGAL STREAMING PORN WITH THIS 24/7 VIDEO ALSO WORKING FOR BALTIMORE POLITICAL MACHINES. GETTING REVENGE AGAINST A REAL LEFT SOCIAL PROGRESSIVE DEMOCRAT.
HOSTING SERVER NOSY NEIGHBOR as BARBER SURGEON thought all this was FUNNY.
Electrically-induced smells pave way for "cochlear implant for the nose"
By Ben Coxworth
November 27, 2018
The study involved stimulation of the olfactory bulb, depicted here as the bulb visible behind the eye
Cochlear implants allow deaf people to hear by electrically stimulating their auditory nerves, and have been doing so for years. While that's all very well and good, what about people who have lost their sense of smell? Well, new research suggests that we may be getting closer to an electrical implant for them, too.
In a study conducted by scientists at the Harvard-affiliated Massachusetts Eye and Ear institute, five test subjects had electrodes endoscopically placed within their sinus cavity. Aged 43 to 72 years old, all of the people had an intact ability to smell, which was confirmed by a 40-item smell identification test.
WHAT I AM FEELING IN MY NOSE LEADING ME TO CONSTANTLY TOUCH IT ----IS THIS ELECTRICAL STIMULATION ----NO DOUBT BEING APPLIED AT DIFFERENT TIMES OF DAY ---AT LOW OR HIGH STIMULATION.
Those electrodes were subsequently used to stimulate nerves connected to each individual's olfactory bulb, which is a part of the brain that processes and relays smell information from the nose. When this happened, three of the participants reported scents such as those of onions and antiseptic, along with sour and fruity aromas – the perception of these odors was artificially induced by the electrical stimulation.
Based on these results, the researchers now hope that implanted devices could someday detect various smell molecules entering the nose, and respond by stimulating the olfactory bulb accordingly. The technology would specifically be aimed at people who are unable to smell due to nerve damage, as other causes of anosmia (loss of the sense of smell) can often be treated by other means.
"There's currently so little that we can do for these patients, and we hope to eventually be able to reestablish smell in people who don't have a sense of smell," says Dr. Eric Holbrook, corresponding author of a paper on the study. "Now we know that electrical impulses to the olfactory bulb can provide a sense of smell — and that's encouraging."
The paper was recently published in the International Forum of Allergy and Rhinology.
Source: Massachusetts Eye and Ear
When I went into surgery for the broken leg and installation of an ANKLE PLATE------I heard as I was going under anesthesia ========WE WILL GO IN THROUGH THE NOSE------
I ended with an ANKLE PLANT with micro-arrays for VITAL SIGNS----an UPDATE on already installed COCHLEAR AND RETINAL IMPLANTS/BATTERIES----and this NOSE/SINUS IMPLANT.
Now, if that doesn't weaken a human's natural emotions/psychology----they are likely NOT MENTALLY ILL.
'A proof of concept established
Now with established proof of concept, doors have opened for a ‘cochlear implant for the nose’ to be developed in parallel with the work on nerve regeneration. Dr. Holbrook and his team do caution that the concept of an olfactory stimulator is more challenging than existing technologies, however'.
Given the fact that MY NOSE has driven me CRAZY both physically damaging my inner and outer nose structure but also the irritation ----inflammation---constant mucal discharge---I would say to MR HOLBROOK ------
YOU DO NOT HAE PROOF OF CONCEPT-----IT IS NOT ESTABLISHED NO MATTER HOW MANY MEDICAL PAPERS AND FAKE DATA YOU RELEASE.
A Cochlear Implant for the Nose
Thursday, Sep 19, 2019 Research Findings
by Mass. Eye and Ear Communications
Proof-of-concept research may accelerate the development of smell restoration technology.
Estimated to occur in five percent of the population, anosmia is a phenomenon that reduces and/or eliminates a person’s ability to smell.
In some instances of smell loss, there is a treatable, underlying cause that’s easy to pin down, such as sinus disease. Treating the root of the problem typically restores the ability to smell. In other cases, however, anosmia is caused by damage to sensory nerves for which there are currently no proven therapies.
According to Eric Holbrook, MD, director of Rhinology at Massachusetts Eye and Ear, we attribute such cases to the nasal cavity (olfactory) nerves not functioning properly.
Developing regenerative therapies
Olfactory nerves have the ability to regenerate on their own, but this doesn’t always happen.
“Similar to investigators attempting to regenerate hair cells to help those who cannot hear, we are searching for a means to restore the nerves of the nose to induce smell,” Dr. Holbrook said. “Just like regenerating hair cells, restoring the sense of smell in humans will take time.”
Microscopic view of layers of olfactory neurons (red) and one population of basal stem cells (green).
Electrically stimulating the nose
While investigators work on hair cell regeneration, patients with profound hearing loss do have the option of cochlear implants, which are surgically implanted devices that restore hearing.
Taking the cochlear implant as inspiration, Dr. Holbrook’s colleagues from the Virginia Commonwealth University (VCU) School of Medicine have been testing the idea of an olfactory implant system that uses electrodes to stimulate smell.
To determine if this technology is feasible, Dr. Holbrook became the first person to apply an artificial electrical stimulation of smell through the human nasal cavities and sinuses. In a recent study published in International Forum of Allergy & Rhinology, Dr. Holbrook describes that three of five patients reported sensations of smell as a result of the stimulation.
“Our work shows that smell restoration technology is an idea worth studying further,” Dr. Holbrook commented. “The development of cochlear implants, for example, didn’t really accelerate until someone placed an electrode in the cochlea of a patient and found that the patient heard a sound of some type.”
A proof of concept establishedNow with established proof of concept, doors have opened for a ‘cochlear implant for the nose’ to be developed in parallel with the work on nerve regeneration. Dr. Holbrook and his team do caution that the concept of an olfactory stimulator is more challenging than existing technologies, however.
“There’s currently so little that we can do for patients with smell loss, and we hope to eventually be able to re-establish their sense of smell,” Dr. Holbrook said. “Now that we know that electrical impulses to the olfactory bulb can provide a sense of smell, that’s encouraging.”
Eric Holbrook, MD, specializes in complex sinus and endoscopic skull base surgery. He sees patients at the Mass. Eye and Ear Sinus Center, located at our main campus in Boston.